Host and Virus Face Off over RNA Modification

Host and Virus Face Off over RNA Modification

Apr 15, 2019 | Non classé

What happens when a mechanism meant to protect the cell gets exploited by bad-mannered viruses? 11.04.2019 Human cells infected with a CMV virus (green), in a control sample and in cells missing enzymes belonging to the m6A system (center and right) Viruses can be...
In Search of the First Enzymes

In Search of the First Enzymes

Apr 1, 2019 | Non classé

Proto-enzymes designed in the lab bound strongly to RNA and DNA, suggesting a surprising origin for these proteins 01.04.2019 Structural models derived from NMR data. (Upper) The observed major C-PLoop conformation. (Lower) Alignment of the β-(P-loop)-α elements of...
Same Microbe, Different Effect

Same Microbe, Different Effect

Mar 29, 2019 | Non classé

Asking a different question about the bacteria in our microbiomes might help target disease more precisely 27.03.2019 Seemingly identical bacteria may harbor genetic differences that affect the host-microbiome relationship Our gut microbiome – the complement of...
Making Room for Change: Stem Cell Fate Depends on It

Making Room for Change: Stem Cell Fate Depends on It

Mar 27, 2019 | Non classé

Remodeling the power plants known as mitochondria are key to stem cell differentiation 25.03.2019 Mouse embryonic stem cells viewed with a spinning-disc confocal microscope. The levels of a nuclear protein called Nanog (cyan), which keeps these cells in their stem...